Article

Genome wide association analysis in dilated cardiomyopathy reveals two new key players in systolic heart failure on chromosome 3p25.1 and 22q11.23

2020-02-28

Abstract excerpt

<h4>Summary</h4> We present the results of the largest genome wide association study (GWAS) performed so far in dilated cardiomyopathy (DCM), a leading cause of systolic heart failure and cardiovascular death, with 2,719 cases and 4,440 controls in the discovery population. We identified and replicated two new DCM-associated loci, one on chromosome 3p25.1 (lead SNP rs62232870, p = 8.7 × 10 −11 and 7.7 × 10 −4 i...

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Literature Corpus work: 0f68eb84-b743-58a1-82b4-089d486bbd46
DOI: 10.1101/2020.02.28.969147

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