Article

Genome-wide association analysis reveals insights into the molecular etiology underlying dilated cardiomyopathy

2023-09-29

Abstract excerpt

Dilated cardiomyopathy (DCM) is a clinical disorder characterised by reduced contractility of the heart muscle that is not explained by coronary artery disease or abnormal haemodynamic loading. Although Mendelian disease is well described, clinical testing yields a genetic cause in a minority of patients. The role of complex inheritance is emerging, however the common genetic architecture is relatively unexplored....

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: efadf640-5097-5be8-96c6-d4164379674b
DOI: 10.1101/2023.09.28.23295408

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Genome-wide association analysis reveals insights into the molecular etiology underlying dilated cardiomyopathyDOI 10.1101/2023.09.28.23295408Read

Genome-wide association analysis provides insights into the molecular etiology of dilated cardiomyopathy.Semantic proximity Read

Genome-wide association study reveals mechanisms underlying dilated cardiomyopathy and myocardial resilience.Semantic proximity Read

Shared genetic pathways contribute to risk of hypertrophic and dilated cardiomyopathies with opposite directions of effect.Semantic proximity Read

Dilated cardiomyopathy: the complexity of a diverse genetic architecture.Semantic proximity Read

Genetics of Dilated Cardiomyopathy.Semantic proximity Read

Analysis of cardiac magnetic resonance imaging traits in 29,000 individuals reveals shared genetic basis with dilated cardiomyopathySemantic proximity Read

Genetic Overlap Between Dilated Cardiomyopathy and Neurological Disorders: Insights from a Next-Generation Sequencing StudySemantic proximity Read

Integration of dilated cardiomyopathy genomics with transcriptomics from the human heart implicates regulatory molecular mechanismsSemantic proximity Read

A novel locus for autosomal-dominant dilated cardiomyopathy maps to chromosome 7q22.3-31.1.Semantic proximity Read

Identification of novel genetic risk factors of dilated cardiomyopathy: from canine to human.Semantic proximity Read

Comprehensive review on gene mutations contributing to dilated cardiomyopathySemantic proximity Read

Dilated Cardiomyopathy: Genetic Determinants and Mechanisms.Semantic proximity Read