Article

Single domain antibody-antigen adducts that target Class II MHC induce antigen-specific tolerance

2021-02-11

Abstract excerpt

<title>Abstract</title> <p>The association of autoimmune diseases with particular allelic variants of Class II MHC (MHCII) products implicates presentation of the offending self-antigen(s) to T cells. Antigen presenting cells are tolerogenic when they encounter antigen under non-inflammatory conditions. Manipulation of antigen presentation would therefore be a possible intervention to induce antigen-specific tole...

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Literature Corpus work: 0f02da68-3af6-5f45-96e1-9d5e39012769
DOI: 10.21203/rs.3.rs-192181/v1

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