Article

Malignant cell MHC-II immunopeptidomes reveal the evolution of tumor-host interactions

2025-12-18

Abstract excerpt

<title>Abstract</title> <p>Adaptive immunity to cancer requires effective antigen presentation on Major Histocompatibility Complexes1. While recent advances in identifying cancer-specific MHC-I antigens have ushered in a new era of antigenspecific immunotherapies2-4, studies on MHC-II are less developed due to the lack of robust tools that enable isolation of MHC-II from cell types of interest in physiologically...

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Literature Corpus work: 42e407ff-eb1e-5c05-aa82-db3a9904d595
DOI: 10.21203/rs.3.rs-8264262/v1

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