Article
Immunological tolerance using synthetic peptides--basic mechanisms and clinical application.
Current molecular medicine - 1 Sept 2006
Hochweller Kristin, Sweenie Claire H, Anderton Stephen M
Abstract excerpt
Dysregulation of T lymphocyte function underpins the development of autoimmune and allergic diseases. These autoantigen-, or allergen-reactive pathogenic T cells are rare within the entire immune repertoire and it is therefore desirable to develop more specific therapies than are currently in use to directly target these cells and avoid adverse side effects. The obvious approach is to use the antigens that are...
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