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Article

Modular mRNA platform for <i>in vivo</i> antigen-specific immune tolerance

2026-05-21

Abstract excerpt

Immune-mediated diseases such as autoimmunity and allergy arise from dysregulated antigen-specific responses, yet current therapies largely rely on broad immunosuppression and rarely re-establish durable, antigen-selective tolerance. Here we introduce Tol-mRNA, a modular tolerogenic mRNA platform designed to deliver multiple immune-regulatory signals in vivo to program antigen-specific tolerance. Tol-mRNA co-enco...

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Identifiers and source

Literature Corpus work
82f8b06c-ccdb-58fa-b505-695d27a9c56f
DOI
10.64898/2026.05.18.725807
Open publication

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Modular mRNA platform for <i>in vivo</i> antigen-specific immune toleranceDOI 10.64898/2026.05.18.725807
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