Article

Interfering PTBP1 expression inducing M2 macrophage polarization via miR-124/MAPK pathway

2024-02-21

Abstract excerpt

<title>Abstract</title> <p>Background Modulating the polarization phenotype of macrophages from M1 to M2 type appears to offer significant potential for treating CNS diseases, such as spinal cord injury and stroke. Polypyrimidine tract-binding protein 1 (PTBP1) is an indispensable RNA-binding protein that participates in nearly all stages of RNA maturation, with particular importance in pre-mRNA splicing. Howeve...

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Literature Corpus work: 0ef8ea21-54bd-539d-974d-096dbe948972
DOI: 10.21203/rs.3.rs-3874246/v1

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