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Article

ZBP1 aggravates acute lung injury in mice by promoting the macrophage inflammatory phenotype.

Immunobiology - 1 Jan 2026

Li Hong, Du Xiaoliang, Liu Yongze, Yang Jiawu, Dai Qinglang, Liao Yuan, Li Feng

Abstract excerpt

BACKGROUND: Acute lung injury (ALI) is an acute lung inflammatory disease that is difficult to cure and has a poor prognosis. Macrophages play a key role in the pathogenesis of ALI, and their different phenotypes and functions affect the progression of the disease. This study aimed to explore how ZBP1 affects the progression of ALI via the regulation of macrophage inflammatory phenotype. METHODS: A RAW264.7 cell...

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Share to Acute Lung Injury
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 41496195
DOI: 10.1016/j.imbio.2025.153154

Genes

ZBP1
MPO
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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