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Article

Exosomes-mediated phenotypic switch of macrophages in the immune microenvironment after spinal cord injury.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie - 1 Dec 2021

Peng Peng, Yu Hao, Xing Cong, Tao Bo, Li Chao, Huang Jingyuan, Ning Guangzhi, Zhang Bin, Feng Shiqing

Abstract excerpt

Although accumulating evidence indicated that modulating macrophage polarization could ameliorate the immune microenvironment and facilitate the repair of spinal cord injury (SCI), the underlying mechanism of macrophage phenotypic switch is still poorly understood. Exosomes (Exos), a potential tool of cell-to-cell communication, may play important roles in cell reprogramming. Herein, we investigated the roles of...

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PMID: 34653754
DOI: 10.1016/j.biopha.2021.112311

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