Article
Magnetic resonance imaging and spectroscopic markers for the detection and metabolic characterisation of IDH-mutant gliomas
2021-01-01
Abstract excerpt
Background: The discovery of mutations in the isocitrate dehydrogenase (IDH) 1/2 gene induced a paradigm shift in the determination of diagnosis, prognosis and treatment of glioma. In 2016 the World Health Organisation (WHO) incorporated mutations in IDH1/2 into the diagnostic criteria for intracranial tumours as they have been demonstrated in 70-80% of WHO grade II-III gliomas, as well as in grade IV secondary gl...
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Identifiers and source
- Literature Corpus work
- 7ade6a32-4939-5d07-b910-3e8ec9dfbf7b
- DOI
- 10.17638/03118009