Article

SCDC: Bulk Gene Expression Deconvolution by Multiple Single-Cell RNA Sequencing References

2019-08-22

Abstract excerpt

Recent advances in single-cell RNA sequencing (scRNA-seq) enable characterization of transcriptomic profiles with single-cell resolution and circumvent averaging artifacts associated with traditional bulk RNA sequencing (RNA-seq) data. Here, we propose SCDC, a deconvolution method for bulk RNA-seq that leverages cell-type specific gene expression profiles from multiple scRNA-seq reference datasets. SCDC adopts an...

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Literature Corpus work: 367c7878-3406-5078-9588-7520de649565
DOI: 10.1101/743591

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