Article

MuSiC2: cell type deconvolution for multi-condition bulk RNA-seq data

2022-05-08

Abstract excerpt

<h4>ABSTRACT</h4> Cell type composition of intact bulk tissues can vary across samples. Deciphering cell type composition and its changes during disease progression is an important step towards understanding disease pathogenesis. To infer cell type composition, existing cell type deconvolution methods for bulk RNA-seq data often require matched single-cell RNA-seq (scRNA-seq) data, generated from samples with sim...

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Literature Corpus work: ad46447e-b752-5c9a-9ed9-6344426251fa
DOI: 10.1101/2022.05.08.491077

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