Article
Glioblastoma disrupts cortical network activity at multiple spatial and temporal scales
2022-09-02
Abstract excerpt
The emergence of glioblastoma in cortical tissue initiates early and persistent neural hyperexcitability with signs ranging from mild cognitive impairment to convulsive seizures. The influence of peritumoral synaptic density, growth dynamics, and spatial contours of excess glutamate upon higher order neuronal network modularity is unknown. We combined cellular and widefield imaging of calcium and glutamate fluores...
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Identifiers and source
- Literature Corpus work
- 0deaebca-5856-575b-9957-edd8e027a0d7
- DOI
- 10.1101/2022.08.31.505988