Article

Epileptogenesis dynamics driven by peritumoral circuit rewiring in gangliogliomas

2026-08-10

Abstract excerpt

Gangliogliomas (GGs) are emblematic low-grade epilepsy-associated tumors, yet the developmental mechanisms underlying their epileptogenicity remain unclear. Here, we investigated how tumor-network interactions evolve across postnatal maturation using an in-utero electroporated BRAF V600E -driven mouse model combining multiscale electrophysiology with histology, single-nucleus RNA sequencing, and complementary ana...

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Literature Corpus work: 4e2ef0c4-36b5-5779-a73e-39cb257c0f73
DOI: 10.64898/2026.08.04.742675

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