Article

Aging potentiates glioma-driven remodeling of cortico-hippocampal neuron-astrocyte dynamics

2026-02-11

Abstract excerpt

<title>Abstract</title> <p>Age is the strongest determinant of glioblastoma incidence and outcome, yet how aging shapes the functional consequences of tumor burden across the brain remains unclear. Glioblastoma is accompanied by cognitive and affective dysfunction that implicates disruption of neural networks beyond the tumor core, particularly in the aged state. Here, we show that aging modifies how glioma burde...

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Literature Corpus work: 8b6ac396-aefe-58aa-bcd8-3a5629322619
DOI: 10.21203/rs.3.rs-8725420/v1

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