Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A clinically applicable connectivity signature for glioblastoma includes the tumor network driver CHI3L1

6 Feb 2024

Abstract excerpt

Tumor microtubes (TMs) connect glioma cells to a network with considerable relevance for tumor progression and therapy resistance. However, the determination of TM-interconnectivity in individual tumors is challenging and the impact on patient survival unresolved. Here, we establish a connectivity signature from single-cell RNA-sequenced (scRNA-Seq) xenografted primary glioblastoma (GB) cells using a dye uptake...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Glioma Diagnosis and Treatment
Share to Mathematical Biology Tumor Growth
Share to Single-cell and spatial transcriptomics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38320988
DOI: 10.1038/s41467-024-45067-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A clinically applicable connectivity signature for glioblastoma includes the tumor network driver CHI3L1PMID 38320988Read ↗

A connectivity signature for glioblastomaSemantic proximity Read ↗

Strength of spatial correlation between structural brain network connectivity and brain-wide patterns of proto-oncogene and neural network construction gene expression is associated with diffuse glioma survivalSemantic proximity Read ↗

A human iPSC-based neural spheroid platform for modeling glioblastoma infiltration using high-content imagingSemantic proximity Read ↗

Collective cancer cell calcium activity drives brain metastasisSemantic proximity Read ↗

Modeling glioblastoma invasion using human brain organoids and single-cell transcriptomicsSemantic proximity Read ↗

Ex vivo Dynamics of Human Glioblastoma Cells in a Microvasculature-on-a-Chip System Correlates with Tumor Heterogeneity and Subtypes.Semantic proximity Read ↗

Morphoregulatory ADD3 underlies glioblastoma growth and formation of tumor–tumor connectionsSemantic proximity Read ↗

Glioblastoma cells imitate neuronal excitability in humansSemantic proximity Read ↗

<i>Ex vivo</i> dynamics of human glioblastoma cells in a microvasculature-on-a-chip system correlates with tumor heterogeneity and subtypesSemantic proximity Read ↗

Spatiotemporal Insights into Glioma Oncostream Dynamics: Unraveling Formation, Stability, and Disassembly PathwaysSemantic proximity Read ↗

Genetic, cellular, and connectomic characterization of the brain regions commonly plagued by gliomaSemantic proximity Read ↗

Structural remodeling of tumor microtubes in IDH1 mutation shapes microRNA transfer in glioma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.