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<p class="MDPI12titleori1" style="mso-line-height-alt: 14.0pt;"><span style="mso-bidi-font-size: 18.0pt; mso-ligatures: standardcontextual;">5-ALA/SFC Mitigates Tau Toxicity via Lowering Oxidative Stress in a <em>Drosophila</em> Model of Tau Toxicity

2026-03-10

Abstract excerpt

Mitochondrial dysfunctions are believed to contribute to the pathogenesis of tauopathies, a group of neurodegenerative diseases with abnormal accumulation of microtubule-associated protein tau. The combination of 5-aminolevulinic acid (5-ALA) and sodium ferrous citrate (SFC) is known to improve mitochondrial functions. Here, we report that 5-ALA combined with SFC (5-ALA/SFC) improves mitochondrial functions and mi...

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Literature Corpus work: 0d7af0a2-ff9a-558b-957c-1e8ba34413fc
DOI: 10.20944/preprints202603.0731.v1

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