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Probing Mechanisms That Underlie Human Neurodegenerative Diseases in <i>Drosophila</i>

15 Sept 2012

Abstract excerpt

The fruit fly, Drosophila melanogaster, is an excellent organism for the study of the genetic and molecular basis of metazoan development. Drosophila provides numerous tools and reagents to unravel the molecular and cellular functions of genes that cause human disease, and the past decade has witnessed a significant expansion of the study of neurodegenerative disease mechanisms in flies. Here we review the...

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PMID: 22974305
DOI: 10.1146/annurev-genet-110711-155456

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