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Article

CERTL Reduces C16 Ceramide, Amyloid-β Levels and Inflammation in a Model of Alzheimer's Disease

2020-06-15

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Deregulation of ceramide and sphingomyelinlevels have been suggested tocontribute tothe pathogenesis of Alzheimer’s disease (AD).Ceramide transfer proteins (CERTs) are ceramide carriers, crucial for ceramide and sphingomyelin balance in cells.Extracellular forms of CERTs co-localize with amyloid-β (Aβ) plaques in AD brains. To date, the significance of these obs...

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Literature Corpus work
0d1d3e37-8718-5070-a206-57c878eea1b3
DOI
10.21203/rs.3.rs-33901/v1
Open publication

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CERTL Reduces C16 Ceramide, Amyloid-β Levels and Inflammation in a Model of Alzheimer's DiseaseDOI 10.21203/rs.3.rs-33901/v1
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