Article

Neuroinflammatory transcriptional programs induced in rhesus pre-frontal cortex white matter during acute SHIV infection

2022-06-06

Abstract excerpt

<h4>Background: </h4> Immunosurveillance of the central nervous system (CNS) is vital to resolve infection and injury. However, immune activation within the CNS in the setting of chronic viral infections, such as HIV-1, is strongly linked to progressive neurodegeneration and cognitive decline. Establishment of HIV-1 in the CNS early following infection underscores the need to delineate features of acute CNS immune...

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Literature Corpus work: 547a44be-4af4-5772-b2ec-28b7b9b20c9f
DOI: 10.21203/rs.3.rs-1701344/v1

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