Article

Summary statistics knockoff inference empowers identification of putative causal variants in genome-wide association studies

2021-12-07

Abstract excerpt

Recent advances in genome sequencing and imputation technologies provide an exciting opportunity to comprehensively study the contribution of genetic variants to complex phenotypes. However, our ability to translate genetic discoveries into mechanistic insights remains limited at this point. In this paper, we propose an efficient knockoff-based method, GhostKnockoff, for genome-wide association studies (GWAS) that...

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Literature Corpus work: 0caa89b9-ce77-583b-bb10-4837b12c3fc6
DOI: 10.1101/2021.12.06.471440

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