Back to search

Article

Developmentally dynamic changes in DNA methylation in the human pancreas

2023-10-22

Abstract excerpt

<h4>ABSTRACT</h4> Development of the human pancreas requires the precise temporal control of gene expression via epigenetic mechanisms and the binding of key transcription factors. We quantified genome-wide patterns of DNA methylation in human fetal pancreatic samples from donors aged 6 to 21 post-conception weeks. We found dramatic changes in DNA methylation across pancreas development, with >21% of sites charac...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
0c8562d8-e283-5802-a46e-23ea2763413a
DOI
10.1101/2023.10.19.563104
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Developmentally dynamic changes in DNA methylation in the human pancreasDOI 10.1101/2023.10.19.563104
DNA Methylation Landscapes of Human Fetal DevelopmentSemantic proximity
Spatiotemporal DNA Methylome Dynamics of the Developing Mammalian FetusSemantic proximity
The emerging landscape of dynamic DNA methylation in early childhood.Semantic proximity
Pancreatic Cancer Patient Survival Correlates with DNA Methylation of Pancreas Development GenesSemantic proximity
Characterizing the dynamic and functional DNA methylation landscape in the developing human cortexSemantic proximity
Characterizing the dynamic and functional DNA methylation landscape in the developing human cortexSemantic proximity
The genetic basis for DNA methylation variation across tissues and developmentSemantic proximity
The genetic basis for DNA methylation variation across tissues and development.Semantic proximity
Expanded map of genomic imprinting reveals insight into human diseaseSemantic proximity
A Chromatin Basis for Cell Lineage and Disease Risk in the Human Pancreas.Semantic proximity
Implication of epigenetics in pancreas development and diseaseSemantic proximity
DNA methylation and DNA methyltransferases.Semantic proximity
Select a neighboring publication to make it the new centre.