Article
Characterizing the dynamic and functional DNA methylation landscape in the developing human cortex
2019-10-30
Abstract excerpt
DNA methylation (DNAm) is a key epigenetic regulator of gene expression across development. The developing prenatal brain is a highly dynamic tissue, but our understanding of key drivers of epigenetic variability across development is limited. We therefore assessed genomic methylation at over 39 million sites in the prenatal cortex using whole genome bisulfite sequencing and found loci and regions in which methyla...
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Identifiers and source
- Literature Corpus work
- 501d4c4b-146e-5107-ab77-d46b914b1388
- DOI
- 10.1101/823781