Article
The emerging landscape of dynamic DNA methylation in early childhood.
BMC genomics - 5 Jan 2017
Xu Cheng-Jian, Bonder Marc Jan, Söderhäll Cilla, Bustamante Mariona, Baïz Nour, Gehring Ulrike, Jankipersadsing Soesma A, van der Vlies Pieter, van Diemen Cleo C, van Rijkom Bianca, Just Jocelyne, Kull Inger, Kere Juha, Antó Josep Maria, Bousquet Jean, Zhernakova Alexandra, Wijmenga Cisca, Annesi-Maesano Isabella, Sunyer Jordi, Melén Erik, Li Yang, Postma Dirkje S, Koppelman Gerard H
Abstract excerpt
BACKGROUND: DNA methylation has been found to associate with disease, aging and environmental exposure, but it is unknown how genome, environment and disease influence DNA methylation dynamics in childhood. RESULTS: By analysing 538 paired DNA blood samples from children at birth and at 4-5 years old and 726 paired samples from children at 4 and 8 years old from four European birth cohorts using the Illumina...
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