Article

Modifiers and Mediators of Craniosynostosis Severity Revealed by Differential Gene Expression

2020-01-29

Abstract excerpt

Severity of craniosynostosis in humans varies widely even in patients with identical genetic mutations. In this study we compared RNA sequencing data from cranial tissues of a severe form of Crouzon craniosynostosis syndrome (C57BL/6 FGFR2 C342Y/+ mice) with those of a less severe form of Crouzon craniosynostosis (BALB/c FGFR2 C342Y/+ mice) to identify genetic modifiers that influence craniosynostosis phenotype...

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Literature Corpus work: 0c7516bf-6216-55d6-92dc-2de11c994d44
DOI: 10.1101/2020.01.28.923508

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