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Article

A Genetic-Pathophysiological Framework for Craniosynostosis.

American journal of human genetics - 3 Sept 2015

Twigg Stephen R F, Wilkie Andrew O M

Abstract excerpt

Craniosynostosis, the premature fusion of one or more cranial sutures of the skull, provides a paradigm for investigating the interplay of genetic and environmental factors leading to malformation. Over the past 20 years molecular genetic techniques have provided a new approach to dissect the underlying causes; success has mostly come from investigation of clinical samples, and recent advances in high-throughput...

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Identifiers

PMID: 26340332
DOI: 10.1016/j.ajhg.2015.07.006
PMCID: PMC4564941

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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