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Article

Tissue-specific responses to aberrant FGF signaling in complex head phenotypes.

Developmental dynamics : an official publication of the American Association of Anatomists - 1 Jan 2013

Martínez-Abadías Neus, Motch Susan M, Pankratz Talia L, Wang Yingli, Aldridge Kristina, Jabs Ethylin Wang, Richtsmeier Joan T

Abstract excerpt

BACKGROUND: The role of fibroblast growth factor and receptor (FGF/FGFR) signaling in bone development is well studied, partly because mutations in FGFRs cause human diseases of achondroplasia and FGFR-related craniosynostosis syndromes including Crouzon syndrome. The FGFR2c C342Y mutation is a frequent cause of Crouzon syndrome, characterized by premature cranial vault suture closure, midfacial deficiency, and...

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Identifiers

PMID: 23172727
DOI: 10.1002/dvdy.23903
PMCID: PMC3556393

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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