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Article

The Fgfr2 W290R mouse model of Crouzon syndrome.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery - 1 Sept 2012

Gong S-G

Abstract excerpt

PURPOSE: This study aimed to review and discuss the utility of the Fgfr2 (W290R) mouse mutant as a model of human Crouzon syndrome. METHODS: A review of current and past scientific literature on Fibroblast Growth Factor Receptor-2 (FGFR2) protein domain structure, FGFR mutations associated with human Crouzon syndrome, and phenotypic and molecular changes combined with recent observations and experimental data of...

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Source

Identifiers

PMID: 22872266
DOI: 10.1007/s00381-012-1792-y

Genes

FGFR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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