Article

A Detailed View of KIR Haplotype Structures and Gene Families as Provided by a New Motif-based Multiple Sequence Alignment

2020-08-09

Abstract excerpt

Human chromosome 19q13.4 contains genes encoding killer-cell immunoglobulin-like receptors (KIR). Reported haplotype lengths range from 67 to 269 kilobases and contain 4 to 18 genes. The region has certain properties such as single nucleotide variation, structural variation, homology, and repetitive elements that make it hard to align accurately beyond single gene alleles. To the best of our knowledge, a multiple...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: bd2481c3-5d2b-56fd-8354-a0b8391e6824
DOI: 10.1101/2020.08.07.242305

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

A Detailed View of KIR Haplotype Structures and Gene Families as Provided by a New Motif-based Multiple Sequence AlignmentDOI 10.1101/2020.08.07.242305Read

Revealing Complete Complex <i>KIR</i> Haplotypes Phased by Long-read Sequencing TechnologySemantic proximity Read

Defining KIR and HLA Class I Genotypes at Highest Resolution via High-Throughput Sequencing.Semantic proximity Read

Genetic Diversity and Structural Complexity of the Killer-Cell Immunoglobulin-Like Receptor Gene Complex: A Comprehensive Analysis Using Human Pangenome AssembliesSemantic proximity Read

Genetic complexity of killer-cell immunoglobulin-like receptor genes in human pangenome assemblies.Semantic proximity Read

Efficient Sequencing, Assembly, and Annotation of Human KIR HaplotypesSemantic proximity Read

Human and Rhesus Macaque KIR Haplotypes Defined by Their Transcriptomes.Semantic proximity Read

Accurate and Efficient KIR Gene and Haplotype Inference From Genome Sequencing Reads With Novel K-mer Signatures.Semantic proximity Read

Full resolution HLA and KIR genes annotation for human genome assembliesSemantic proximity Read

Full-resolution HLA and KIR gene annotations for human genome assemblies.Semantic proximity Read

Single haplotype analysis demonstrates rapid evolution of the killer immunoglobulin-like receptor (KIR) loci in primates.Semantic proximity Read

High-Resolution Characterization of KIR Genes in a Large North American Cohort Reveals Novel Details of Structural and Sequence Diversity.Semantic proximity Read

Comparative genomic analysis, diversity and evolution of two KIR haplotypes A and B.Semantic proximity Read