Article

Elements and Evolutionary Determinants of Genomic Divergence Between Paired Primary and Metastatic Tumors

2020-08-25

Abstract excerpt

<h4>ABSTRACT</h4> Can metastatic-primary (M-P) genomic divergence measured from next generation sequencing reveal the natural history of metastatic dissemination? This remains an open question of utmost importance in facilitating a deeper understanding of metastatic progression, and thereby, improving its prevention. Here, we utilize mathematical and computational modeling to tackle this question as well as to pr...

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Literature Corpus work: 0c337041-60da-5e0d-8179-4ce8a9becd79
DOI: 10.1101/2020.08.24.262378

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