Article

PathFinder: Bayesian inference of clone migration histories in cancer

2020-07-10

Abstract excerpt

<h4>Summary</h4> Metastases form by dispersal of cancer cells to secondary tissues. They cause a vast majority of cancer morbidity and mortality. Metastatic clones are not medically detected or visible until later stages of cancer development. Thus, clone phylogenies within patients provide a means of tracing the otherwise inaccessible dynamic history of migrations of cancer cells. Here we present a new Bayesian...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 01fa7311-623a-53c9-ac47-5e89f5ecc55f
DOI: 10.1101/2020.07.10.197194

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

PathFinder: Bayesian inference of clone migration histories in cancerDOI 10.1101/2020.07.10.197194Read

PathFinder: Bayesian inference of clone migration histories in cancer.Semantic proximity Read

Clone Phylogenetics Reveals Metastatic Tumor Migrations, Maps, and ModelsSemantic proximity Read

Inferring parsimonious migration histories for metastatic cancers.Semantic proximity Read

Power and pitfalls of computational methods for inferring clone phylogenies and mutation orders from bulk sequencing dataSemantic proximity Read

Inferring cancer type-specific patterns of metastatic spread using MetientSemantic proximity Read

Modeling metastatic progression from cross-sectional cancer genomics dataSemantic proximity Read

Early and multiple origins of metastatic lineages within primary tumors.Semantic proximity Read

Modeling metastatic progression from cross-sectional cancer genomics data.Semantic proximity Read

Reconstructing metastatic seeding patterns of human cancers.Semantic proximity Read

Power and pitfalls of computational methods for inferring clone phylogenies and mutation orders from bulk sequencing data.Semantic proximity Read

Single-cell lineages reveal the rates, routes, and drivers of metastasis in cancer xenografts.Semantic proximity Read

Using tumour phylogenetics to identify the roots of metastasis in humans.Semantic proximity Read