Article

Modeling metastatic progression from cross-sectional cancer genomics data

2024-01-31

Abstract excerpt

Metastasis formation is a hallmark of cancer lethality. Yet, metastases are generally unobservable during their early stages of dissemination and spread to distant organs. Genomic datasets of matched primary tumors and metastases may offer insights into the underpinnings and the dynamics of metastasis formation. We present metMHN, a cancer progression model designed to deduce the joint progression of primary tumor...

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Literature Corpus work: 45ef223c-fcc0-585c-87ce-053c85f11480
DOI: 10.1101/2024.01.30.577989

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