Article

Comparing the effect profile of cholesteryl ester transfer protein (CETP) in individuals of East Asian and European ancestries

2023-08-16

Abstract excerpt

<title>Abstract</title> <p>CETP is a lipid drug target under development for coronary heart disease (CHD) in both European and East Asian populations. Previous drug target Mendelian randomization (MR) studies conducted in East Asians failed to show a CHD effect, which has been interpreted as lack of effectiveness of CETP inhibition for CHD prevention in this population. Nevertheless, CETP inhibitors are currently...

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Literature Corpus work: 1d55f70c-d58e-5660-820a-1cc6f5cce961
DOI: 10.21203/rs.3.rs-3184550/v1

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