Article

Evaluating and Improving Health Equity and Fairness of Polygenic Scores

2023-09-24

Abstract excerpt

Polygenic scores (PGS) are quantitative metrics for predicting phenotypic values, such as human height or disease status. Some PGS methods require only summary statistics of a relevant genome-wide association study (GWAS) for their score. One such method is Lassosum, which inherits the model selection advantages of Lasso to select a meaningful subset of the GWAS single nucleotide polymorphisms as predictors from t...

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Literature Corpus work: 0bfc8925-cfc3-533f-81fa-afc8a04ad9cd
DOI: 10.1101/2023.09.22.559051

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