Article
PGS-server: accuracy, robustness and transferability of polygenic score methods for biobank scale studies.
Briefings in bioinformatics - 10 Mar 2022
Yang Sheng, Zhou Xiang
Abstract excerpt
Polygenic scores (PGS) are important tools for carrying out genetic prediction of common diseases and disease related complex traits, facilitating the development of precision medicine. Unfortunately, despite the critical importance of PGS and the vast number of PGS methods recently developed, few comprehensive comparison studies have been performed to evaluate the effectiveness of PGS methods. To fill this...
Topics
- Biological Specimen Banks
- Genome-Wide Association Study
- Multifactorial Inheritance
- Phenotype
- Sample Size