Article

FairPRS: a fairness framework for Polygenic Risk Scores

2022-08-30

Abstract excerpt

Polygenic risk scores (PRS) are increasingly used to estimate the personal risk of a trait based on genetics. However, most genomic cohorts are of European populations, with strong under-representative of multi-ethnic minority groups. Given that PRS poorly transport across racial groups, this has the potential exacerbate health disparities if used in clinical care. Hence there is a need to generate PRS that perfor...

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Literature Corpus work: 4d7ae97e-e0a9-556c-a6c3-0b2b02a9b188
DOI: 10.1101/2022.08.28.22279309

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