Article

Alternative Lengthening of Telomeres is not synonymous with mutations in ATRX/DAXX

2020-05-07

Abstract excerpt

The PCAWG Consortium has recently released an unprecedented set of tumor whole genome sequence (WGS) data from 2,658 cancer patients across 38 different primary tumor sites 1 . WGS is able to document the quantity and distribution of telomeric repeats 2 . In one of the papers analyzing the PCAWG dataset, Sieverling et al. 3 confirmed previous data 4 indicating that tumors with truncating ATRX or DAXX alteratio...

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Literature Corpus work: 0bd1a699-04fb-53d3-addd-63b142a282e2
DOI: 10.1101/2020.05.05.076125

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