Article

Reliable assessment of telomere maintenance mechanisms in neuroblastoma

2022-06-03

Abstract excerpt

<title>Abstract</title> <p>Background: Telomere maintenance mechanisms (TMM) are a hallmark of high-risk neuroblastoma, and are conferred by activation of telomerase or alternative lengthening of telomeres (ALT). However, detection of TMM is not yet part of the clinical routine, and consensus on TMM detection, especially on ALT assessment, remains to be achieved. <h4>Methods:</h4> Whole genome sequencing (WGS) d...

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Literature Corpus work: 8fb495ab-f13a-5d08-b72d-5cede514d5bc
DOI: 10.21203/rs.3.rs-1704872/v1

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