Article

Structural and mechanistic views of enzymatic, heme-dependent nitrogen-nitrogen bond formation

2023-12-15

Abstract excerpt

<h4>Summary</h4> Molecules with nitrogen-nitrogen (N-N) bonds constitute a large group of clinically important drugs, and various synthetic approaches have been developed to construct functional groups like hydrazines, diazos, pyrazoles, and N-nitrosos. While hundreds of N-N-containing specialized natural metabolites have also been discovered, little is known about the underlying enzymatic mechanisms that have ev...

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Literature Corpus work: 0b791d56-e2eb-5a57-b508-5c1bb548b5bc
DOI: 10.1101/2023.12.15.571702

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