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Article

Novel dehydrogenase catalyzes oxidative hydrolysis of carbon-nitrogen double bonds for hydrazone degradation.

The Journal of biological chemistry - 29 Feb 2008

Itoh Hideomi, Suzuta Tetsuya, Hoshino Takayuki, Takaya Naoki

Abstract excerpt

Hydrazines and their derivatives are versatile artificial and natural compounds that are metabolized by elusive biological systems. Here we identified microorganisms that assimilate hydrazones and isolated the yeast, Candida palmioleophila MK883. When cultured with adipic acid bis(ethylidene hydrazide) as the sole source of carbon, C. palmioleophila MK883 degraded hydrazones and accumulated adipic acid...

Topics

Aldehyde Dehydrogenase
Amino Acid Sequence
Candida
Fungal Proteins
Hydrazones
Hydrolysis
Kinetics
Molecular Sequence Data
Mutation
NADP
Oxidation-Reduction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Protein Structure, Quaternary

Saccharomyces cerevisiae

Soil Microbiology

Substrate Specificity

Source

Identifiers

PMID: 18096698
DOI: 10.1074/jbc.M709027200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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