Article

INFIMA leverages multi-omics model organism data to identify effector genes of human GWAS variants

2021-07-15

Abstract excerpt

Genome-wide association studies have revealed many non-coding variants associated with complex traits. However, model organism studies have largely remained as an untapped resource for unveiling the effector genes of non-coding variants. We develop INFIMA, In tegrative Fi ne- Ma pping, to pinpoint causal SNPs for Diversity Outbred (DO) mice eQTL by integrating founder mice multi-omics data including ATAC-seq, R...

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Literature Corpus work: 0b6ea424-a6fe-5cc2-b749-06ce56c1eb47
DOI: 10.1101/2021.07.15.452422

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