Article

CHCHD4 regulates a proliferation-EMT switch in tumour cells, through respiratory complex I mediated metabolism

2019-01-07

Abstract excerpt

<h4>ABSTRACT</h4> <h4>BACKGROUND</h4> Mitochondrial metabolism involves oxidative phosphorylation (OXPHOS) via the respiratory chain and is required for the maintenance of tumour cell proliferation and regulation of epithelial–mesenchymal transition (EMT)-related phenotypes through mechanisms that are not fully understood. The essential mitochondrial import protein coiled-coil helix coiled-coil helix domain-cont...

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Literature Corpus work: 0b450717-fc20-5ad4-86cc-5a7ef5b808b2
DOI: 10.1101/513531

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