Article
Metabolic reprogramming and epithelial-to-mesenchymal transition in cancer.
The FEBS journal - 1 Oct 2017
Sciacovelli Marco, Frezza Christian
Abstract excerpt
Several lines of evidence indicate that during transformation epithelial cancer cells can acquire mesenchymal features via a process called epithelial-to-mesenchymal transition (EMT). This process endows cancer cells with increased invasive and migratory capacity, enabling tumour dissemination and metastasis. EMT is associated with a complex metabolic reprogramming, orchestrated by EMT transcription factors,...
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