Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mitochondrial Dysfunction: A Novel Potential Driver of Epithelial-to-Mesenchymal Transition in Cancer

30 Nov 2017

Abstract excerpt

Epithelial-to-mesenchymal transition (EMT) allows epithelial cancer cells to assume mesenchymal features, endowing them with enhanced motility and invasiveness, thus enabling cancer dissemination and metastatic spread. The induction of EMT is orchestrated by EMT-inducing transcription factors that switch on the expression of "mesenchymal" genes and switch off the expression of "epithelial" genes. Mitochondrial...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy in Disease and Therapy
Share to Cancer, Hypoxia, and Metabolism
Share to Mitochondrial Function and Pathology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29250487
DOI: 10.3389/fonc.2017.00295

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mitochondrial Dysfunction: A Novel Potential Driver of Epithelial-to-Mesenchymal Transition in CancerPMID 29250487Read ↗

Mitochondria act as a key regulatory factor in cancer progression: Current concepts on mutations, mitochondrial dynamics, and therapeutic approach.Semantic proximity Read ↗

Mitochondria and the hallmarks of cancer.Semantic proximity Read ↗

Current and upcoming mitochondrial targets for cancer therapy.Semantic proximity Read ↗

The Significance of Mitochondrial Dysfunction in Cancer.Semantic proximity Read ↗

Mitochondria and Cancer.Semantic proximity Read ↗

Multifaceted roles of mitochondrial dysfunction in diseases: from powerhouses to saboteurs.Semantic proximity Read ↗

Mitochondrial remodeling in colorectal cancer initiation, progression, metastasis, and therapy: A reviewSemantic proximity Read ↗

The Role of Mitochondrial Dynamics and Mitophagy in Carcinogenesis, Metastasis and TherapySemantic proximity Read ↗

Mitochondria and cancer.Semantic proximity Read ↗

Mitochondria and cancer: past, present, and future.Semantic proximity Read ↗

Dysregulation of mitophagy in carcinogenesis and tumor progression.Semantic proximity Read ↗

Mitochondrial dysfunctions in cancer: genetic defects and oncogenic signaling impinging on TCA cycle activity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.