Article

Cell type deconvolution of bulk blood RNA-Seq to reveal biological insights of neuropsychiatric disorders

2023-05-25

Abstract excerpt

Genome-wide association studies (GWAS) have uncovered susceptibility loci associated with psychiatric disorders like bipolar disorder (BP) and schizophrenia (SCZ). However, most of these loci are in non-coding regions of the genome with unknown causal mechanisms of the link between genetic variation and disease risk. Expression quantitative trait loci (eQTL) analysis of bulk tissue is a common approach to decipher...

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Literature Corpus work: 0b423ace-8b64-5dbb-aa10-e1a1f8569539
DOI: 10.1101/2023.05.24.542156

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