Article

EPIC: inferring relevant cell types for complex traits by integrating genome-wide association studies and single-cell RNA sequencing

2021-06-10

Abstract excerpt

More than a decade of genome-wide association studies (GWASs) have identified genetic risk variants that are significantly associated with complex traits. Emerging evidence suggests that the function of trait-associated variants likely acts in a tissue- or cell-type-specific fashion. Yet, it remains challenging to prioritize trait-relevant tissues or cell types to elucidate disease etiology. Here, we present EPIC...

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Literature Corpus work: 7eedff31-429f-58a0-aaa3-584b6eddaddb
DOI: 10.1101/2021.06.09.447805

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