Article

Neuregulin-1 Regulates the Conversion of M1/M2 Microglia Phenotype via ErbB4-dependent Inhibition of the NF-κB Pathway

2021-12-02

Abstract excerpt

<title>Abstract</title> <p>BackgroundThe inflammatory response caused by microglia in the central nervous system plays an important role in Alzheimer's disease. Neuregulin-1 (NRG1) is a member of the neuregulin family and has been demonstrated to have anti-inflammatory properties. The relationship between NRG1, microglia phenotype and neuroinflammation remains unclear.Materials and MethodsBV2 cells were used to e...

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Literature Corpus work: 0b308c00-9013-5ffb-8daf-de3b4ad29fb4
DOI: 10.21203/rs.3.rs-1117291/v1

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