Article

The secretome of M1 and M2 microglia differently regulate proliferation, differentiation and survival of adult neural stem/progenitor cell

2021-09-16

Abstract excerpt

Microglia has been reported to be able to regulate the proliferation, differentiation and survival of adult Neural stem/progenitor cells (NSPCs) by modulating the microenvironment, which results in different consequences of adult neurogenesis. However, whether the microglial activation is beneficial or harmful to NSPCs is still controversial because of the complexity and variability of microglial activation phenot...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 13e52188-8883-5423-a765-8bf796b35fec
DOI: 10.1101/2021.09.15.460424

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The secretome of M1 and M2 microglia differently regulate proliferation, differentiation and survival of adult neural stem/progenitor cellDOI 10.1101/2021.09.15.460424Read

Modulating the polarization phenotype of microglia - A valuable strategy for central nervous system diseases.Semantic proximity Read

Selective proliferative response of microglia to alternative polarization signals.Semantic proximity Read

Microglia as therapeutic target in central nervous system disorders.Semantic proximity Read

The tri-culture system reveals an activation cascade from microglia through astrocytes to neurons during neuroinflammationSemantic proximity Read

Heterogeneity of Microglia Phenotypes: Developmental, Functional and Some Therapeutic ConsiderationsSemantic proximity Read

Alternatively activated microglia and macrophages in the central nervous system.Semantic proximity Read

Characterization of phenotype markers and neuronotoxic potential of polarised primary microglia in vitro.Semantic proximity Read

Bone marrow-derived mesenchymal stem cells maintain the resting phenotype of microglia and inhibit microglial activation.Semantic proximity Read

Interferon regulatory factor 7 participates in the M1-like microglial polarization switch.Semantic proximity Read

Microglia regulate adult neurogenesis via interleukin-6 trans-signaling triggered by apoptotic progenitorsSemantic proximity Read

PBM Combined with hUCMSCs Modulates the Polarization of MicrogliaSemantic proximity Read

Microglia Polarization from M1 toward M2 Phenotype Is Promoted by Astragalus Polysaccharides Mediated through Inhibition of miR-155 in Experimental Autoimmune Encephalomyelitis.Semantic proximity Read