Back to search

Article

Mesenchymal stem cell-derived exosomes inhibit Aβ1-42 induced microglia polarization by TLR2/MYD88/NF-κB pathway

2021-04-22

Abstract excerpt

<title>Abstract</title> <p>Background In recent years, more and more research evidence indicates that the causes of various neurodegeneration diseases are related to neuroinflammation in the brain, Aβ1–42 may be a key factor in the development of neuroinflammation in neurodegenerative diseases. Therefore, it is urgent to find an effective and targeted alleviation of neuroinflammation caused by Aβ1–42. Methods O...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
6cc9a461-6f53-5569-8760-e7bb4f6f78ba
DOI
10.21203/rs.3.rs-416793/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Mesenchymal stem cell-derived exosomes inhibit Aβ1-42 induced microglia polarization by TLR2/MYD88/NF-κB pathwayDOI 10.21203/rs.3.rs-416793/v1
Microglia-derived exosomes selective sorted by YB-1 alleviate nerve damage and cognitive outcome in Alzheimer’s diseaseSemantic proximity
Modulating the polarization phenotype of microglia - A valuable strategy for central nervous system diseases.Semantic proximity
Bone marrow mesenchymal stem cell-derived exosomes attenuate cerebral ischemia-reperfusion injury-induced neuroinflammation and pyroptosis by modulating microglia M1/M2 phenotypes.Semantic proximity
Microglia Polarization from M1 toward M2 Phenotype Is Promoted by Astragalus Polysaccharides Mediated through Inhibition of miR-155 in Experimental Autoimmune Encephalomyelitis.Semantic proximity
Astrocyte-derived exosomes enriched with miR-873a-5p inhibit neuroinflammation via microglia phenotype modulation after traumatic brain injurySemantic proximity
Advanced Therapies for Traumatic Central Nervous System Injury: Delivery Strategy Reinforced Efficient Microglial Manipulation.Semantic proximity
Exosome-shuttled miRNAs contribute to the modulation of the neuroinflammatory microglia phenotype by mesenchymal stem cells. Implication for amyotrophic lateral sclerosisSemantic proximity
PBM Combined with hUCMSCs Modulates the Polarization of MicrogliaSemantic proximity
Exploring New Inflammatory Biomarkers and Pathways during LPS-Induced M1 Polarization.Semantic proximity
Interleukin-37 modulates microglial phenotype and inhibits inflammatory response via the MyD88/NF-κB pathway in Lipopolysaccharide-induced neuroinflammationSemantic proximity
Bu Shen Yi Sui Capsule Alleviates Neuroinflammation and Demyelination by Promoting Microglia toward M2 Polarization, Which Correlates with Changes in miR-124 and miR-155 in Experimental Autoimmune Encephalomyelitis.Semantic proximity
Human breast milk-derived exosomes attenuate lipopolysaccharide-induced upregulation of CD40 and NLRP3 in microgliaSemantic proximity
Select a neighboring publication to make it the new centre.