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Article

Discovering the genes mediating the interactions between chronic respiratory diseases in the human interactome.

Nature communications - 10 Feb 2020

Maiorino Enrico, Baek Seung Han, Guo Feng, Zhou Xiaobo, Kothari Parul H, Silverman Edwin K, Barabási Albert-László, Weiss Scott T, Raby Benjamin A, Sharma Amitabh

Abstract excerpt

The molecular and clinical features of a complex disease can be influenced by other diseases affecting the same individual. Understanding disease-disease interactions is therefore crucial for revealing shared molecular mechanisms among diseases and designing effective treatments. Here we introduce Flow Centrality (FC), a network-based approach to identify the genes mediating the interaction between two diseases...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Pulmonary Disease, Chronic Obstructive

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Source

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Identifiers

PMID: 32041952
DOI: 10.1038/s41467-020-14600-w
PMCID: PMC7010776

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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